Personal Bio
Linlin is a Post-Doctoral Fellow and joined Dr. Xiao’s lab in August of 2020. He received his Ph.D. in Analytical Chemistry from the Institute of Chemistry, Chinese Academy of Sciences. In his free time, he enjoys fitness training, hiking, and he has a preference for spicy food.
Research Summary
Linlin’s research focuses primarily on the selection of high-affinity and high-specificity aptamers for small-molecules, as well as the development of novel screening methods. At present, he is dedicated to the selection of highly specific aptamers for estradiol.
Publications List
- Canoura J., Alkhamis O., Byrd C., Wang L., Bryant A., & Xiao Y. (2024). Determining the Precision of High-Throughput Sequencing and Its Influence on Aptamer Selection. Anal. Chem. 96, 17720-17729
- Wang L., Canoura J., Byrd C., Nguyen T., Alkhamis O., Ly P., & Xiao Y. (2024). Examining the Relationship between Aptamer Complexity and Molecular Discrimination of a Low-Epitope Target. ACS Cent. Sci. 10, 2213 – 2228.
- Wang L. L., Alkhamis O., Canoura J., Yu H. X. & Xiao Y. (2024) Rapid nuclease-assisted selection of high-affinity small-molecule aptamers. J. Am. Chem. Soc. 146, 21296 – 21307.
- Alkhamis O., Canoura J., Wang L. L. & Xiao Y. (2024) Nuclease-assisted selection of slow-off rate aptamers. Sci. Adv. 10, eadl3426.
- Alkhamis O., Canoura J., Willis C., Wang L.L., Perry, J. & Xiao Y. (2023) Comparison of aptamer signaling mechanisms reveals disparities in sensor response and strategies to eliminate false signals. J. Am. Chem. Soc. 145, 12407 – 12422.
