The experimental results of this project (15PNIJ-22-GG-04440-RESS) are reported in the publications listed below. These DOIs are associated with links to the articles and their supporting information. The data can be found in the publications.

  • Wang L.L., Castro G., Alkhamis O., Gangireddy M.S.R., Bukhryakov K.V., Vinueza N.R. & Xiao Y. (2026) A selective, class-specific aptamer for fentanyl analog screening. Anal. Chem. https://doi.org/10.1021/acs.analchem.6c03173
ASelective,Class-SpecificAptamerforFentanylAnalogScreeningDownload
  • Nguyen T., Bacon A., Alkhamis O., Venzke M., Hill R., Castro G., Byrd C., Bukhryakov K.V., Jun Ohata J., Millbern Z., Vinueza N.R., Xiao Y. (2026) A broadly generalizable dye for colorimetric aptamer-based sensors. JACS Au. https://doi.org/10.1021/jacsau.6c00703
A broadly generalizable dye for colorimentric apamer-based sensorDownload
  • Byrd C., Alkhamis O., Castro G., Nguyen T., Canoura, J., Xiao Y. (2026) High-throughput aptamer characterization via real-time nuclease digestion. J. Am. Chem. Soc. 148, 10421 – 10436.
High-throughput aptamer characterization via real time nuclease digestionDownload
  • Nguyen T., Alkhamis O., Bacon A., Bukhryakov K.V., Vinueza N.R., Xiao Y. (2025) High-contrast aptamer-based merocyanine displacement assay for sensitive small molecule detection. ACS Sens. 10, 7799 – 7809.
High contrast aptamer-based merocyanine displacement assays for sensitive small molecule detectionDownload
  • Alkhamis O., Byrd C., Canoura J., Bacon A., Hill R., Xiao Y. (2025) Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity. Nucleic Acids Res. 53, gkaf219.
Exploring the relationship between aptamer binding thermodynamics, affinity, and specificityDownload
  • Yu H. X., Canoura J., Byrd C., Alkhamis O., Bacon A., Yan A., Sullenger B.A., Xiao Y. (2025) Improving aptamer affinity and determining sequence-activity relationships via motif-SELEX. J. Am. Chem. Soc. 147, 9472 – 9486.
Improving aptamer affinity and determining sequence activity relationships via motif SELEXDownload
  • Wang L.L., Canoura J., Byrd C., Nguyen T., Alkhamis O., Ly P. Xiao Y. (2024) Examining the relationship between aptamer complexity and molecular discrimination of a low-epitope target. ACS Cent. Sci. 10, 2213 – 2228.
Examining the relationship between aptamer complexity and molecular discrimination of a low epitope targetDownload
  • Canoura J., Alkhamis O., Venzke M., Ly P.T., Xiao Y. (2024) Developing aptamer-based colorimetric opioid tests. JACS Au 4, 1059 – 1072.
Developing aptamer-based colorimetric opioid testsDownload
  • Canoura J., Liu Y.Z., Alkhamis O., Xiao Y. (2023) Aptamer-based fentanyl detection in biological fluids. Anal. Chem. 95, 18258 – 18267.
Aptamer-based fentanyl detection in biological fluidsDownload
  • Summary of conferences and meetings for NIJ Supported Research – 15PNIJ-22-GG-04440-RESS:
Summary of conferences and meetingsDownload